WORK PACKAGE ARCHITECTURE

Context:

Gene and cellular therapies are complex products that require comprehensive and ongoing training of health care professionals as well as patients and caregivers. A plethora of training courses are already offered by Marketing Authorisation Holders (MAHs) as well as health organisations, which can lead to considerable overlap.

Overall aim:

Develop harmonised educational programmes for different groups of health care professionals (HCPs) and patients.

Current work groups/activities:

• Webinar series:
  • GoCART Clinical Case Discussion series for physicians
  • GoCART Nurses Best Practice Sharing session
• Map CAR T manufacturers’ educational training requirements for HCPs and develop a core CAR T curriculum.
• Develop CAR T-cell therapy Clinician Checklists to contribute to improvements in the quality and safety of medical care.

Main achievements to date:

• In the Clinical Case Discussion series for physicians, two clinical cases were presented and discussed in each webinar with a panel of CAR T experts. The aim was to discuss real-life clinical cases as instructive examples, foster lateral thinking to meeting participant’s own cases, contribute to a broader understanding of CAR T treatments, toxicity management and outcomes. Ten sessions and twenty clinical cases were discussed in 2022.
• The Nurses Best Practice Sharing Sessions focused on different aspects of the patient journey and/or the care nurses provide. In the sessions, a nurse expert presented the theoretical background information and a real-life case. Six sessions were held in 2022.
• Both webinar series are on hold as we develop new e-learning modules for the future.
• GoCART has started discussions with industry partners to explore harmonisation of training requirements. We aim to consolidate a “core” training for HCPs, with industry partners providing additional product specific training. This would be tailored to each HCP role, i.e. doctors, nurses, etc., and would act as a passport specific to the individual – in the same way a driver’s license is specific to an individual. Therefore, the trained/qualified individual can move between centres and only require additional product specific training.